Description
Product Characteristics:
Converts noradrenaline to adrenaline.
Subcellular location: Cytoplasm
Synonyms: PENT, PNMTase, Phenylethanolamine N-methyltransferase, Noradrenaline N-methyltransferase, PNMT
Target Information: The product of this gene catalyzes the last step of the catecholamine biosynthesis pathway, which methylates norepinephrine to form epinephrine (adrenaline). The enzyme also has beta-carboline 2N-methyltransferase activity. This gene is thought to play a key step in regulating epinephrine production. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Nov 2012]